Songwriter Roger Radcliffe lives in a bachelor flat in London, England along with his dalmatian
Pongo. Bored with bachelor life, Pongo decides to find a wife for Roger
and a mate for himself. While watching various female dog-human pairs
out the window, he spots the perfect couple, a woman named Anita and her
female dalmatian, Perdita. He quickly gets Roger out of the house and
drags him through the park to arrange a meeting. Pongo accidentally
causes both Roger and Anita to fall into a pond, but it works out well
as the couple falls in love. Both couples marry.
Later, Perdita gives birth to 15 puppies. One almost dies, but Roger
is able to revive it by rubbing it in a towel. That same night, they are
visited by Cruella De Vil,
a wealthy and materialistic former schoolmate of Anita's. She offers to
buy the entire litter for a large sum, but Roger says they are not for
sale. Weeks later, she hires Jasper and Horace Badun to steal them. When
Scotland Yard is unable to determine the thieves or find the puppies, Pongo and Perdita use the "Twilight Bark", normally a canine gossip line, to ask for help from the other dogs in London.